a blue screen again? (the firmware upgrade is to be expected for each software update)
I cannot see why changing the runtime/axoloti app would alter your driver setup.
I (still) think you have some conflicting driver/device/software... and you should follow the steps i detailed in my earlier post to try to determine the cause of conflict. its telling (to me), no other users have reported the issue, again pointing to a particular aspect of your setup.
I don't know what you use the machine for... but if its not 'mission critical', perhaps now is a good time to think about the windows 10 upgrade, and do it as a completely fresh install. (i.e don't preserve settings, this always carried over loads of rubbish and usually issues).
I don't run windows (except in VMs) these days, but when I did, I used to do fresh installs every 12-18 months, because of the mess windows into... and i see little evidence its got any better
Note: Im only a volunteer/contributor to Axoliti, so this is just what I would do... and not any kind of 'official' response or recommendation on whats necessary, as I recognise this might be seen as an 'extreme' action - but personally I loathe unstable systems.
proper recommendations can only come from Johannes, who obviously knows Axoloti inside out.